Course catalogue
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Master SERP+ Programme - cohort 2020-2025
Introduction to biophysics and microscopies for life science (5 ECTS)
Semester 1
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All courses during this semester
Semester 2
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All courses during this semester
- Transferable skills: Polish course, Summer School in Entrepreneurship (6 ECTS)
- The molecules of life: from structure to chemical function (3 ECTS)
- Selected in silico and in vitro methods in thermodynamics and soft matter (6 ECTS)
- Organic chemistry (3 ECTS)
- Introduction to solid state (6 ECTS)
- Dynamics of photochemical reactions in chemistry, biology and medicine (6 ECTS)
- Transferable skills: Portuguese course, Summer School in Entrepreneurship (6 ECTS)
- Solid State Physics (6 ECTS)
- Molecular Energetics (3 ECTS)
- Laboratory of Materials and Surface Analysis (6 ECTS)
- Interfacial Electrochemistry (3 ECTS)
- Interfaces, Colloids and Self-Assembly (6 ECTS)
- Transferable skills: Summer School in Entrepreneurship (3 ECTS)
- Organic Photochemistry (3 ECTS)
- Italian Courses (3 ECTS)
- Introduction to Solid State (6 ECTS)
- Inorganic Functional Materials (3 ECTS)
- Electrochemical systems for energy conversion and storage (6 ECTS)
- Chemistry and Technology of Catalysis and Laboratory (6 ECTS)
Semester 3
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All courses during this semester
- Transferable skills: Scientific writing, French courses - 5ECTS
- Nanosciences (6 ECTS)
- Nanoparticles and Advanced radiation therapies (6 ECTS)
- Fundamentals in data science and machine learning (3 ECTS)
- Femtochemistry (3 ECTS)
- Chemistry for renewable energy: from advanced research to industrial applications (6 ECTS)
- Transferable skills: Scientific writing, Polish courses (6 ECTS)
- Lanthanide luminescence: Application in chemistry and biology (6 ECTS)
- Introduction to Data Sciences (3 ECTS)
- Environmental photochemistry (3 ECTS)
- Computational and quantum photochemistry (6 ECTS)
- Applied photochemistry and luminescence spectroscopy (6 ECTS)
- Scientific Writing and Career Objectives (3 ECTS)
- Portuguese course (3 ECTS)
- Nanotechnologies, Micro and Nano-fabrication (6 ECTS)
- Materials Properties and Applications (6 ECTS)
- Electrochemical Technology (6 ECTS)
- Data Science Basics (3 ECTS)
- Bionanotechnology (3 ECTS)
- Transferable skills: Scientific Writing Industrial Seminars (3 ECTS)
- Surface Science and Nanostructuring at Surfaces (6 ECTS)
- Polymers for electronics and energy harvesting (6 ECTS)
- Laboratory on device building (3 ECTS)
- Italian Courses (3 ECTS)
- Data Science and Applications to Chemistry (3 ECTS)
- Composite materials for biomedical applications (6 ECTS)
Content
Introduction to biology: the toolbox for biophysics
- Cell biology (From DNA to proteins, Cell architecture and motility, The Cell cycle)
- Biochemistry (The elementary bricks of life: proteins, DNA, RNA, membrane/lipids)
Biophysics and microscopies for the life sciences
- Optical microscopy: Fluorescence and fluorescent probes for biology, setups for microscopy, super-resolved microscopy techniques, applications to quantitative analysis of molecular behaviors in live cells
- Introduction to Atomic Force Microscopy: Atomic Force Microscopy (AFM): Theory and application of AFM. From cells to single molecule studies (Living cells imaging, DNA imaging, biopolymer elasticity).
Practical courses
- Visualization of cell’s cytoskeleton: The aim of the course is to use the immunofluorescence technique to stain components of the cell (actin filaments, tubulins and microtubules) on fixed cells.
- Bioinformatics: The aim of this course is to learn how to use the PDB website and to visualize protein structures in 3D with VMD.
- Atomic force microscopy: This practical course will teach to student how to use an AFM (imaging and force curve analysis) to study fixed and dried cells (bacteria or eukaryotic cells).
- Spectroscopic analysis of the isomerization of a GFP chromophore: The aim of this practical course is to analyze the molecular events happening in a cyan fluorescent protein upon a pH jump from 7 to 5.
- Data analysis of microscopy data [3h ON, ½ classe] Students will analyze time-resolved recordings of biological parameters. They will use in-situ calibration data to quantify cellular concentrations.
Aims
This course is an introduction to several concepts of Biophysics organized by a multidisciplinary team composed of physico-chemist, physicists and cell biologists. It will focus on microscopies and their application to biology.
Activities in small groups, research related tutorials and hands-on will help to develop critical faculties of the students.
Teaching Staff
Marie Erard (Course Coordinator)
Sophie Dupré
Oliver Nüsse
Ariane Deniset
Hours
Lectures: 10h
Exercises: 8h
Laboratory: 16.5h