Introduction to the standard analysis technics used for chemical analysis of compounds:
- fundamentals of mass spectrometry and main ionization techniques & fragmentations methods,
- UV-vis absorption and fluorescence spectroscopies, IR absorption spectroscopy, application to the characterization of molecules and to analytical chemistry,
- Nuclear Magnetic Resonance spectroscopy: principles using the vectorial model, different interactions, application to the determination of compound structures.
- Part A: Mass Spectrometry
- Part B: Optical spectroscopies & Photophysical processes
- I. When molecules and light meet…
- II. Electronic transitions – UV-visible and fluorescence
- III. Rovibrational spectroscopy – IR spectroscopy
- IV. Nuclear Magnetic Resonance (NMR)
- Mass spectrometry study on gas-phase protonated peptides
- Fluorimetry: Polyatomic molecules in condensed phase
- Infrared spectroscopy: Rotation vibration spectra of CO and HCl
- Nuclear Magnetic Resonance
- To gain an overview on the standard methods of optical spectroscopy (IR, UV-vis, fluo, NMR): associated spectral ranges, probed molecular properties, applications in analytical chemistry.
- To understand the fundamental photochemical processes.
- To gain knowledge about the chemical analysis of compounds using mass spectrometry.
- Physical Chemistry, P. Atkins & J. de Paula
- Spectrometric Identification of Organic Compounds, 7th Edition, R.M. Silverstein, F.X. Webster, D. Kiemle
- Mass spectrometry, a textbook, J.H. Gross
- Molecular Fluorescence: Principles and Applications, B. Valeur
- Photochemistry, C.E. Wayne & R.P. Wayne
- NMR spectroscopy, Harald Gunther (John Wiley & Sons)
- Chemical Analysis: Modern Instrumentation Methods and Techniques, A. Rouessac and F. Rouessac
- NuclearMagneticResonance, P.J.Hore
- Understanding NMR, J.Keller