Chemical reaction. Mechanism; breaking and creating chemical bonds
simultaneus breaking and bonding
Classification of reactions: addition, elimination, substitution, condensation rearrangement, pericyclic reactions.
Rearrangements towards electron-deficient atom (C, N, O). Wagner-Meerwein, pinacol, Hofmann, Curtius, Schmidt, Lossen rearrangements, Bayer-Villiger oxidation.
Rearrangements towards electron-rich carbon atom (Favorskii, Stevens)
Elements of stereochemistry. Strategy of asymmetric synthesis
Pericyclic reactions, orbital symmetry considerations.
Catalysis in organic chemistry.
Heterocyclic compounds. Five- and six-membered rings containing N, S and O atoms. Biologically relevant heterocyclic compounds.
Aminoacids, peptides, proteins
Knowledge of chemical properties of different classes of organic compounds, methods of their synthesis. Mechanistic interpretations of the expriment results. Knowledge of relation between structure and properties.
Knowledge and understanding of basic topics of organic chemistry. Ability to interpret reaction mechanism and plan the synthetic route of given organic compound.
- John McMurry Organic chemistry Brooks/Cole Publishing
- L.G Wade Organic chemistry Pearson Prentice Hall
- Paula Yurkanis Bruice Organic chemistry 5th edition Pearson Prentice Hall